PerkinElmer

Quantitative Pathology Research

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Better understand the interactions between tumor cells and the immune system within the tumor microenvironment. Our Phenoptics quantitative pathology solutions for cancer immunology and immunotherapy research in tissue includes:

  • Advanced multiplex immunohistochemistry staining kits
  • Multispectral imaging and whole slide scanning instruments
  • Image analysis software
  • Contract research services

For detecting multiple biomarkers in situ and enabling a deeper understanding of the biology of cancer, learn more about the Phenoptics Quantitative Pathology Research Solution.

Tumor Microenvironment Opal 7 Color Image
Tumor Microenvironment Opal 7 Color Image

Stain

Simultaneously detect six biomarkers plus DAPI within a single tissue section. Similar to standard immunohistochemistry, our advanced method is accessible to many laboratories where IHC method development is performed. It allows researchers to use the best primary antibodies, even those raised in the same species, together for multiplex detection. Our staining solutions provide researchers with tools to assess multiple cellular phenotypes at the same time while retaining context provided within tissue sections.
Vectra® Polaris™ Automated Quantitative Pathology Imaging System
Vectra® Polaris™ Automated Quantitative Pathology Imaging System

Image

Our quantitative pathology imaging systems deliver high quality data where morphological context is preserved down to the sub-cellular level, removing autofluorescence and increasing signal-to-noise. These systems detect and measure multiple biomarkers, even if overlapping, within a single IHC or IF tissue section or TMA. Low signal levels that were previously undetected can now be captured, and overall quantification is vastly improved - particularly for solid, formalin-fixed, and paraffin-embedded tissues.
inform Image Analysis Software for Digital Pathology
inform Image Analysis Software for Digital Pathology

Analyze

Our software programs combine the latest technologies with algorithms and intuitive, easy-to-use interfaces, giving you the power to make new, exciting discoveries from your data. Our automated advanced image analysis software allows you to visualize, analyze, quantify and phenotype cells labeled with multiple biomarkers in situ in FFPE tissue sections.
Contract Research Services for Phenotyping In Situ
Contract Research Services for Phenotyping In Situ

Contract Research Services

Interested in testing the Phenoptics™ workflow? Our Research Services team can perform multiplexed IHC for up to seven colors (six markers plus DAPI) to help you get results.
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Product Type
  • Accessories (12)
  • Instruments (3)
  • Reagents (9)
  • Software and Informatics (2)
Application
  • Immunohistochemistry (IHC) (4)
Assay Target
  • CD20 (3)
  • CD4 (4)
  • CD45RO (1)
  • CD68 (2)
  • CD8 (4)
  • FOXP3 (2)
  • panCK (2)
Automation Compatible
  • No (4)
  • Yes (1)
Detection Method
  • Brightfield (2)
  • Fluorescence (6)
  • MSI (3)
Fluorophore
  • Opal 520 (4)
  • Opal 540 (3)
  • Opal 570 (4)
  • Opal 620 (3)
  • Opal 650 (3)
  • Opal 670 (1)
  • Opal 690 (3)
Imaging Modality
  • Multispectral Imaging (4)
Product Brand Name
  • Mantra (1)
  • Opal (7)
  • Vectra Polaris (1)
Target Species
  • Human (4)
Technology
  • Multiplexed Biomarker Imaging (1)
Type
  • Opal 520 (1)
  • Opal 540 (1)
  • Opal 570 (1)
  • Opal 620 (1)
  • Opal 650 (1)
  • Opal 690 (1)

"Quantitative Pathology Research" 1-26 of 26 Products and Services

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Mantra benchtop

Mantra Quantitative Pathology Workstation

Mantra quantitative pathology workstation with inForm® image analysis software enables easy visualization, quantification and phenotyping of multiple types of immune cells simultaneously in intact FFPE tissue sections for cancer immunology research.
Vectra Polaris with monitor

Vectra Polaris Automated Quantitative Pathology Imaging System

The Vectra® Polaris Automated Quantitative Pathology Imaging System integrates both multispectral imaging and automated slide scanning to better visualize, analyze, quantify, and phenotype immune cells in situ in FFPE tissue sections and TMAs.
Vectra image

Vectra 3.0 Automated Quantitative Pathology Imaging System

The Vectra® 3 automated quantitative pathology imaging system accurately detects and measures weakly expressing and overlapping biomarkers within a single H&E, IHC or IF intact FFPE tissue section or TMA.
PerkinElmer

Opal 7 Immunology Discovery Panel Kit

The Opal™ 7 Immunology Discovery Kit enables phenotyping of T cells, B cells and macrophages, with 3 open channels for user-selected targets.
List Price : 3350.00 CAD
Opal 650 Reagent Pack

Opal Reagent Packs

Opal is a practical workflow for simultaneous detection of up to 6 tissue biomarkers plus nuclear counterstain, within a single image. The method is similar to standard immunohistochemistry and is accessible to many laboratories where standard IHC method development is performed.
Price Range : 145.00 CAD - 165.00 CAD
PerkinElmer

Opal 4 Lymphocyte Panel Kit

The Opal™ 4 Tumor Lymphocyte Kit enables phenotyping of helper T cells, cytotoxic T cells and B cells within intact FFPE tissue sections.
List Price : 2000.00 CAD
Opal Spectral DAPI

Spectral DAPI

This ready-to-use nucleic acid stain has been optimized specifically for Opal and TSA® Plus immunohistochemistry protocols.
List Price : 70.00 CAD
PerkinElmer

Opal Multiplex Manual IHC Kit 50 slides

Opal is a practical workflow for the simultaneous detection of up to six tissue biomarkers plus nuclear counterstain within a single image. The method is similar to standard immunohistochemistry (IHC) and is accessible to many laboratories where standard IHC method development is performed.
Price Range : 1150.00 CAD - 1450.00 CAD
1X Plus Amplification Diluent

1X Plus Amplification Diluent

This patented, ready-to-use amplification diluent has been optimized specifically for Opal and TSA® Plus immunohistochemistry protocols. Used in conjunction with Opal or TSA Plus, the diluent facilitates signal amplification localized to the area of the target.
List Price : 550.00 CAD
Opal 7-Color Automation IHC Kit 50 slides - NEL801001KT

Opal Automation IHC Kit 50 slides

Opal is a practical workflow for the simultaneous detection of up to six tissue biomarkers plus nuclear counterstain within a single image. The method is similar to standard immunohistochemistry (IHC) and is accessible to many laboratories where standard IHC method development is performed.
Price Range : 1050.00 CAD - 1400.00 CAD
PerkinElmer

Opal 7 Solid Tumor Immunology Kit

The Opal™ 7 Solid Tumor Immunology Kit enables phenotyping of helper T cells, cytotoxic T cells, B cells, macrophages and cancer cells within intact FFPE tissue sections.
List Price : 4250.00 CAD
PerkinElmer

Opal 7 Tumor Infiltrating Lymphocyte Kit

The Opal™ Tumor Infiltrating Lymphocyte Kit enables phenotyping of T cells, B cells and cancer cells within intact FFPE tissue sections.
List Price : 4250.00 CAD
PerkinElmer
inForm monitor

inForm Cell Analysis

inForm® Cell Analysis enables quantitative per cell analysis of immunohistochemistry (IHC), immunofluorescence (IF), and RNA in-situ hybridization, enabling the separation of weak and spectrally overlapping markers, in single and multiplex assays.
inForm monitor

inForm Tissue Finder

inForm® Tissue Finder adds exceptional functionality to inForm Cell Analysis to automate the detection and segmentation of specific tissues through powerful patented pattern recognition algorithms. Automation provides consistent reproducible results and enables comparative studies of multiple markers and specimens, supporting researchers to make faster discoveries of the indicators of disease.

"Quantitative Pathology Research" 1-26 of 26 Products and Services