PerkinElmer

Cancer Immunotherapy & Immunology

OF

Immuno-oncology has emerged as an exciting area of personalized medicine because of its tremendous potential to harness the powerful immune system to target and destroy cancer cells with few side effects, when targeted to the right tumor at the right time. Researchers are exploring the complex relationship between tumor cells and the immune system within the tumor microenvironment in order to discover new immuno-oncology targets and therapies.

Research Tools

Our cancer immunotherapy research solutions span the entire drug discovery workflow, from drug screening to studies in pre-clinical animal models to imaging of human tumor samples in clinical trials.

  • Immunoassays and reagents
  • Plate readers
  • Advanced multiplex tissue staining kits
  • Image analysis software
  • Quantitative pathology imaging systems
  • High content imaging and analysis
  • In Vivo imaging
  • Contract services

Kits and Reagents for Immuno-Oncology Research

Targeting immune checkpoint inhibitors, such as PD-1, PD-L1, and CTLA-4, has become pivotal in immunotherapy research, and so have monoclonal antibodies (mAbs), whether naked or conjugated with a chemotherapy agent or radioactive particle. Another area of active investigation is chimeric antigen receptor (CAR) T-cell therapy, where T cells are genetically programmed to attach to proteins on the surface of cancer cells. We offer a number of reagent technologies, radioactive and non-rad, for detection of key immuno-oncology targets.
Vectra 3 200 slide
Vectra 3 200 slide

Instrumentation for Immuno-Oncology Research

With our full suite of immuno-oncology products and solutions––including instrumentation and software for in vitro, ex vivo and in vivo models––we enable rapid and targeted discoveries in cancer immunotherapy.
Phenoptics Research Services
Phenoptics Research Services

Contract Services for Immuno-Oncology Research

Looking for an assay that’s not commercially available? Ask us about our custom services for immuno-oncology research including custom labeling of biomolecules, full assay development and transfer, and tissue imaging and analysis.
  • Products and Services

  • Resources, Events & More

Narrow your results
Product Type
  • Accessories (78)
  • Consumables (4)
  • Instruments (18)
  • Reagents (184)
  • Software and Informatics (12)
Application
  • cAMP (2)
  • Drug Discovery & Development (2)
  • Epigenetics (1)
  • Immunohistochemistry (IHC) (25)
  • In situ hybridization (ISH) (25)
  • In vivo imaging (1)
  • Molecular Biology (8)
  • Protein Analysis & Detection (87)
  • Protein-protein interactions (1)
Assay Points
  • 100 (21)
  • 10000 (15)
  • 500 (52)
  • 5000 (38)
Assay Target
  • A1AT (2)
  • AFP (1)
  • BCL-2 (2)
  • Bcl2 (2)
  • BMP-7 (2)
  • BMP-9 (2)
  • CA125 (1)
  • Caspase-3 (1)
  • Claudin 7 (2)
  • COL1A1 (3)
  • COX-2 (4)
  • CXCL11 (1)
  • E-Cadherin (4)
  • EGF (3)
  • EGFR (5)
  • ErbB2 (3)
  • Factor VIII (1)
  • Fibrinogen (2)
  • Fibronectin (4)
  • HGFR (1)
  • Histone H4 (1)
  • IFNβ (1)
  • Laminin (2)
  • MMP-12 (2)
  • MMP-7 (2)
  • MMP1 (1)
  • MMP2 (1)
  • MMP3 (2)
  • MMP8 (2)
  • MMP9 (2)
  • N-cadherin (2)
  • Oncostatin M (2)
  • p53 (1)
  • PD-1 (4)
  • PD-L1 (2)
  • Perlecan (2)
  • PIP Collagen (2)
  • PSA (1)
  • PTEN (4)
  • TDP-43 (1)
  • TFF3 (1)
  • TGF-β1 (1)
  • TNFα (1)
  • α-tubulin (2)
  • β-NGF (1)
Assay Target Class
  • Collagen (1)
  • Cytokine (6)
  • GPCR (5)
  • Histone (1)
  • Protein (78)
  • Receptor (2)
Assay Validated
  • Binding (3)
  • Calcium Fluorescence (1)
  • Calcium Luminescence (2)
  • cAMP (2)
  • Downstream Phosphorylation (1)
  • GTPγS (2)
Automation Compatible
  • Yes (91)
Buffer
  • Tricine with stabilizer and dye (8)
Concentration
  • 10 mCi/mL (7)
Detection Method
  • Alpha (57)
  • Brightfield (2)
  • Chromogenic (6)
  • Fluorescence (30)
  • Radiometric (9)
  • Time-Resolved Fluorescence (TRF) (31)
  • TR-FRET (31)
  • Transmission (3)
Experimental type
  • In vitro (88)
Fluorescent agent type
  • Activatable (8)
  • Targeted (15)
  • Vascular (5)
Fluorophore
  • Coumarin (1)
  • Cy3 (8)
  • Cy3.5 (1)
  • Cy5 (4)
  • Cy5.5 (1)
  • Fluorescein (6)
  • TMR (5)
Format
  • Microplates (79)
  • Slides (25)
Host Cell
  • CHO-K1 (5)
Imaging Modality
  • Bioluminenscence (20)
  • Fluorescence (27)
  • microCT Imaging (2)
  • Optical Imaging (9)
  • PET Imaging (2)
Label Position
  • alpha (6)
  • gamma (2)
  • Nominally Labeled (1)
Model Compatible With
  • Titan Microwave System (1)
Nucleotide
  • ATP (2)
  • CTP (1)
  • dATP (1)
  • dCTP (1)
  • dTTP (1)
  • GTP (1)
  • UTP (1)
Product Brand Name
  • AequoScreen (1)
  • AequoZen (1)
  • AlphaLISA (45)
  • Ancillary Products (2)
  • Bioware Brite (20)
  • cAMPZen (1)
  • Cat B FAST (2)
  • EasyTide (7)
  • FMT (3)
  • FolateRSense (1)
  • G-Platform (2)
  • HypoxiSense (1)
  • IntegriSense (3)
  • IVIS (6)
  • LANCE Ultra (30)
  • Mantra (1)
  • Membrane Target Systems (1)
  • MMPSense (3)
  • NEN Radiochemicals (2)
  • Opal (3)
  • Opera (1)
  • Opera Phenix (8)
  • Operetta (30)
  • Operetta CLS (1)
  • OsteoSense (3)
  • ProSense (3)
  • Quantum (1)
  • Superhance (1)
  • TLectinSense (1)
  • TSA (12)
  • TSA Plus (14)
  • ValiScreen (1)
  • Vectra Polaris (1)
  • XenoLight (5)
Product Group
  • Vessels and Spares (1)
Radionuclide
  • 33P (8)
  • 3H (1)
Radioisotope
  • H-3 (1)
  • P-33 (8)
Receptor Type
  • Adenosine (5)
Target Species
  • Human (86)
  • Mouse (2)
Technology
  • Multiplexed Biomarker Imaging (1)
Therapeutic Area
  • Angiogenesis (10)
  • Arthritis (20)
  • Atherosclerosis (16)
  • Cancer (81)
  • Cardiovascular (5)
  • Central Nervous System (5)
  • Epigenetics (1)
  • Inflammation (23)
  • Metabolic (5)
  • Oncology/Cancer (27)
  • Vascular disease (5)
Type
  • Opal 520 (1)
  • Opal 540 (1)
  • Opal 570 (1)
  • Opal 620 (1)
  • Opal 650 (1)
  • Opal 690 (1)
Volume
  • 0-50 (13)
  • 51-100 (6)
  • 201-250 (6)
  • 351-400 (1)
  • 451-500 (16)
  • Over 500 (16)
Volume Capacity
  • 150 µL (2)

"Cancer Immunotherapy & Immunology" 1-50 of 296 Products and Services

Sort
Per Page
Vectra_ImageA

Vectra 3.0 Automated Quantitative Pathology Imaging System

The Vectra® 3 automated quantitative pathology imaging system accurately detects and measures weakly expressing and overlapping biomarkers within a single H&E, IHC or IF intact FFPE tissue section or TMA.
Vectra Polaris with monitor

Vectra Polaris Automated Quantitative Pathology Imaging System

The Vectra® Polaris Automated Quantitative Pathology Imaging System integrates both multispectral imaging and automated slide scanning to better visualize, analyze, quantify, and phenotype immune cells in situ in FFPE tissue sections and TMAs.
IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

IVIS Lumina XRMS In Vivo Imaging System

Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.

Operetta High-Content Imaging System

As scientists grapple with increasingly complex biological questions, they need to conduct larger, more complex imaging experiments. So they’re turning to the Operetta® High Content Imaging System – the ideal solution for analyzing the inner workings of healthy and diseased cells.
 
FMT In Vivo Imaging Instrument

FMT 4000 In Vivo Imaging System

The FMT 4000 fluorescence tomography imaging system provides the greatest utility of the FMT Systems with the ability to quantitate up to four fluorophores simultaneously. It comes with four excitation laser channels (635, 680, 750, & 790 nm).
G8 PET/CT benchtop scanner for preclinical imaging research

G8 PET/CT Preclinical Imaging System

Ultrasensitive and fast multimodal preclinical PET/CT imaging at your benchtop. The G-Platform offers Full Solutions for PET Imaging  and includes the G4 and G8 imaging systems.
G4 Preclinical PET benchtop scanner with integrated X-ray

G4 PET/X-ray Preclinical Imaging System

Ultrasensitive and fast multimodal PET/X-ray imaging at your benchtop. The G-Platform offers and includes the G4 and G8 imaging systems.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina III In Vivo Imaging System

The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
FMT In Vivo Imaging Instrument

FMT 1000 In Vivo Imaging System

The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
320X320-Operetta_still_image_35Sec

Operetta CLS High-Content Analysis System

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS™ high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS™ lets you find even subtle phenotypic changes.
IVIS SpectrumCT 2D/3D Optical/CT In Vivo Imaging System

IVIS SpectrumCT In Vivo Imaging System

The IVIS® SpectrumCT preclinical in vivo imaging system expands upon the versatility and advanced optical feature sets of the IVIS platform integrated with low dose microCT to support longitudinal imaging.
IVIS SpectrumBL High Throughput Optical Imaging System

IVIS Spectrum In Vivo Imaging System

The IVIS® Spectrum in vivo imaging system uses a novel patented optical imaging technology to facilitate non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.

Opera Phenix High-Content Screening System

The Opera Phenix™ High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina LT In Vivo Imaging System

The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
Mantra benchtop

Mantra Quantitative Pathology Workstation

Mantra quantitative pathology workstation with inForm® image analysis software enables easy visualization, quantification and phenotyping of multiple types of immune cells simultaneously in intact FFPE tissue sections for cancer immunology research.
Quantum GX microCT Imaging System

Quantum GX microCT Imaging System

With microCT imaging systems, speed and resolution are usually a two-system tradeoff – until now. Gain a better understanding of disease and its progression with combined high-speed, low-dose x-ray, and high-resolution microCT imaging in one instrument.
 
FMT In Vivo Imaging Instrument

FMT 2000 In Vivo Imaging System

The FMT 2000 is a workhorse 3D fluorescence tomographic system with the ability to quantitate up to two fluorophores simultaneously.
IVIS SpectrumBL High Throughput Optical Imaging System

IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.

HGFR/c-MET (human) AlphaLISA Detection Kit

The AlphaLISA® Human HGFR / c-MET Detection Kit is designed for detection and quantitation of HGFR / c-MET in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. The antibodies target the extracellular domain of HGFR. The analyte in this kit consists of the extracellular domain of human HGFR fused to the Fc region of human IgG1.
Price Range : 3450.00 CAD - 27000.00 CAD
AlphaLISA immunoassay kits

EGFR (human) AlphaLISA Detection Kit

The AlphaLISA® EGFR Detection Kit is designed for detection and quantitation of human Epidermal Growth Factor Receptor (EGFR) in cell culture media, human serum, and other sample types using a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 820.00 CAD - 11900.00 CAD
Protein

COX-2 (human), liquid (LANCE)

Human COX-2 standard, for use in running standard curves in LANCE Ultra TR-FRET assays. This standard is already provided in the LANCE Ultra Human COX-2 TR-FRET Detection Kit, but can also be ordered separately.
List Price : 350.00 CAD
Opal Spectral DAPI

Spectral DAPI

This ready-to-use nucleic acid stain has been optimized specifically for Opal and TSA® Plus immunohistochemistry protocols.
List Price : 70.00 CAD
In vivo Fluorescent Agents

MMPSense 680 Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
List Price : 730.00 CAD

RediJect 2-DG Fluorescent Imaging Probe (Standard kit)

XenoLight RediJect 2-DeoxyGlucosone (DG) 750 is a fluorescent imaging probe for in vivo targeting of tumors that typically exhibit elevated glucose uptake rate in comparison to surrounding tissues. To achieve maximum glucose targeting and enhanced tumor uptake, the probe has been designed to contain four 2-DG molecules per dye molecule.  
List Price : 580.00 CAD
AlphaLISA immunoassay kits

MMP-9 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Matrix Metalloproteinase-9 (MMP9) Detection Kit is designed for detection and quantitation of human MMP9 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. The kit was designed to detect both MMP9 and pro-MMP9.
Price Range : 1800.00 CAD - 12000.00 CAD
AlphaLISA immunoassay kits

MMP-9 (mouse) AlphaLISA Detection Kit

The AlphaLISA® Mouse Matrix Metalloproteinase-9 (MMP9) Detection Kit is designed for detection and quantitation of murine MMP9 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. The kit was designed to detect both MMP9 and pro-MMP9.
Price Range : 3450.00 CAD - 27000.00 CAD

Fibronectin (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Fibronectin Detection Kit is designed for detection and quantitation of human fibronectin in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 940.00 CAD - 12600.00 CAD
AlphaLISA immunoassay kits

Alpha-fetoprotein (human) AlphaLISA Detection Kit

The AlphaLISA® Human Alpha-Fetoprotein (AFP) Detection Kit is designed for detection and quantitationof human AFP in cell culture medium and serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1800.00 CAD - 12000.00 CAD

COX-2 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human COX-2 Detection Kit is designed for detection and quantitation of human COX-2 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 920.00 CAD - 12200.00 CAD
AlphaLISA immunoassay kits

E-Cadherin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human E-cadherin enables the detection and quantitation of human E-cadherin in serum, buffered solution, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 530.00 CAD - 11500.00 CAD

BCL-2 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for BCL-2 enables the detection and quantitation of human BCL-2 in serum, buffered solution, or cell culture medium using a homogeneous AlphaLISA assay (no wash steps). This kit is not cross reactive with mouse Bcl-2.
Price Range : 740.00 CAD - 24000.00 CAD
PerkinElmer

TSA Plus Cyanine 3.5

TSA® Plus Cyanine 3.5 (Cy3.5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy3.5 in the localized area of the probe or antibody.
Price Range : 290.00 CAD - 2350.00 CAD
Protein

ErbB2 (human), lyophilized (LANCE)

Human ErbB2 (HER2) standard, lyophilized, for use in running standard curves in LANCE TR-FRET no-wash detection assays. This standard is already provided in the LANCE Ultra Human ErbB2 TR-FRET Detection Kit, but can be ordered separately.
List Price : 280.00 CAD
AlphaLISA immunoassay kits

Perlecan (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human perlecan enables the detection and quantitation of human perlecan (endorepellin) in human serum and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay showed no cross reacitivity to vimentin, fibronectin, nidogen-1, laminin, or collagen I.
Price Range : 530.00 CAD - 11500.00 CAD

PD-L1 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human PD-L1 Detection Kit is designed for detection and quantitation of human PD-L1 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 920.00 CAD - 12200.00 CAD

dATP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxyadenosine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 630.00 CAD - 1600.00 CAD

COX-2 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human COX-2 enables the detection and quantitation of human COX-2 in cell culture supernatants and cell extracts using a homogeneous AlphaLISA assay (no wash steps). The assay shows no cross-reactivity with human COX-1 nor with sheep COX-2.
Price Range : 5000.00 CAD - 37000.00 CAD
AlphaLISA immunoassay kits

PTEN (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human PTEN enables the detection and quantitation of human PTEN in tissue homogenates and cell lysates using a homogeneous AlphaLISA assay (no wash steps). Other species of PTEN were not tested, but detection is expected with mouse and rat PTEN due to >99% sequence homology.
Price Range : 540.00 CAD - 11900.00 CAD
PerkinElmer

TSA Plus DIG Evaluation Kit

TSA® Plus DIG detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra DIG in the localized area of the probe or antibody.
Price Range : 280.00 CAD - 1850.00 CAD

MMP-3 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human MMP-3 Detection Kit is designed for detection and quantitation of human matrix metalloproteinase-3 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 940.00 CAD - 12600.00 CAD

BCL-2 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human BCL-2 Detection Kit is designed for detection and quantitation of human Bcl-2 in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 940.00 CAD - 12600.00 CAD
AlphaLISA immunoassay kits

Fibronectin (human plasma) AlphaLISA Detection Kit

The AlphaLISA® Human Plasma Fibronectin Detection Kit is designed for detection and quantitation of human plasma fibronectin (hFN) in human serum, plasma, and, cell lysate, cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 530.00 CAD - 11500.00 CAD
AlphaLISA immunoassay kits

N-cadherin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human N-cadherin enables the detection and quantitation of human N-Cadherin in tissue homogenates and cell lysates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 540.00 CAD - 11900.00 CAD
In vivo Fluorescent Agents

OsteoSense 680EX Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
List Price : 600.00 CAD
AlphaLISA immunoassay kits

Mucin-16 (Ovarian carcinoma antigen CA125) (human) AlphaLISA Detection Kit

The AlphaLISA® Human Mucin-16 / Ovarian Carcinoma Antigen CA125 (CA125) Detection Kit is designed for detection and quantitation of human CA125 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1800.00 CAD - 12000.00 CAD
LANCE-bromodomain-binding

LANCE Ultra BRD4 (BD1)/H4K5,8,12,16Ac Kit

This kit is designed for the detection of binding activity between bromodomain-containing protein 4, Bromodomain1: BRD4 (BD1) and acetylated histone H4 peptide (H4 K5,8,12,16Ac) using a homogeneous LANCE Ultra TR-FRET assay (no wash steps). The assay allows screening of BRD4 inhibitors with a highly-specific substrate.
Price Range : 920.00 CAD - 12200.00 CAD
AlphaLisa Analyte 2

E-Cadherin (human), lyophilized (AlphaLISA)

Human E-cadherin standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human E-cadherin Detection Kit, but can be ordered separately.
List Price : 280.00 CAD
In vivo Fluorescent Agents

Cat B 680 FAST Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications.  
List Price : 730.00 CAD
PerkinElmer

TSA Plus Cyanine 5

TSA® Plus Cyanine 5 (Cy5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy5 in the localized area of the probe or antibody.
Price Range : 290.00 CAD - 2350.00 CAD

MMP-8 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human MMP-8 enables the detection and quantitation of human MMP-8 in human serum or cell culture medium using a homogeneous AlphaLISA assay (no wash steps). The kit was designed to detect both MMP8 and pro-MMP8.
Price Range : 530.00 CAD - 11500.00 CAD

"Cancer Immunotherapy & Immunology" 1-50 of 296 Products and Services

Per Page