PerkinElmer

Cancer Immunotherapy & Immunology

OF

Immuno-oncology has emerged as an exciting area of personalized medicine because of its tremendous potential to harness the powerful immune system to target and destroy cancer cells with few side effects, when targeted to the right tumor at the right time. Researchers are exploring the complex relationship between tumor cells and the immune system within the tumor microenvironment in order to discover new immuno-oncology targets and therapies.

Research Tools

Our cancer immunotherapy research solutions span the entire drug discovery workflow, from drug screening to studies in pre-clinical animal models to imaging of human tumor samples in clinical trials.

  • Immunoassays and reagents
  • Plate readers
  • Advanced multiplex tissue staining kits
  • Image analysis software
  • Quantitative pathology imaging systems
  • High content imaging and analysis
  • In Vivo imaging
  • Contract services

LANCE Detection Kit
LANCE Detection Kit

Kits and Reagents for Immuno-Oncology Research

Targeting immune checkpoint inhibitors, such as PD-1, PD-L1, and CTLA-4, has become pivotal in immunotherapy research, and so have monoclonal antibodies (mAbs), whether naked or conjugated with a chemotherapy agent or radioactive particle. Another area of active investigation is chimeric antigen receptor (CAR) T-cell therapy, where T cells are genetically programmed to attach to proteins on the surface of cancer cells. We offer a number of reagent technologies, radioactive and non-rad, for detection of key immuno-oncology targets.
Vectra 3 200 slide
Vectra 3 200 slide

Instrumentation for Immuno-Oncology Research

With our full suite of immuno-oncology products and solutions––including instrumentation and software for in vitro, ex vivo and in vivo models––we enable rapid and targeted discoveries in cancer immunotherapy.
Contract Research Services for Phenotyping In Situ
Contract Research Services for Phenotyping In Situ

Contract Services for Immuno-Oncology Research

Looking for an assay that’s not commercially available? Ask us about our custom services for immuno-oncology research including custom labeling of biomolecules, full assay development and transfer, and tissue imaging and analysis.

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"Cancer Immunotherapy & Immunology" 1-50 of 338 Products and Services

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FMT In Vivo Imaging Instrument

FMT 1000 In Vivo Imaging System

The FMT® 1000 is an entry level 3D fluorescence tomographic system with the ability to quantitate a single fluorophore at a time.
IVIS SpectrumBL High Throughput Optical Imaging System

IVIS Spectrum In Vivo Imaging System

The IVIS® Spectrum in vivo imaging system uses a novel patented optical imaging technology to facilitate non-invasive longitudinal monitoring of disease progression, cell trafficking and gene expression patterns in living animals.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina LT In Vivo Imaging System

The IVIS® Lumina LT Series III pre-clinical in vivo imaging system offers the industries most sensitive benchtop platform at an entry level price.
Operetta CLS High Content Analysis Instrument

Operetta CLS High-Content Analysis System

Uncover deep biological understanding in your everyday assays and innovative applications using the Operetta CLS high-content analysis system. Featuring a unique combination of technologies, the system delivers all the speed, sensitivity and resolution you need to reveal fine sub-cellular details. And with our simple, powerful Harmony 4.5 software, Operetta CLS lets you find even subtle phenotypic changes.
Vectra Polaris with monitor

Vectra Polaris Automated Quantitative Pathology Imaging System

The Vectra® Polaris Automated Quantitative Pathology Imaging System integrates both multispectral imaging and automated slide scanning to better visualize, analyze, quantify, and phenotype immune cells in situ in FFPE tissue sections and TMAs.
Vectra image

Vectra 3.0 Automated Quantitative Pathology Imaging System

The Vectra® 3 automated quantitative pathology imaging system accurately detects and measures weakly expressed and overlapping biomarkers within a single H&E, IHC or IF intact FFPE tissue section or TMA to accelerate your cancer immunology research.

Opera Phenix High-Content Screening System

The Opera Phenix High Content Screening System is the premier confocal solution for today's most demanding high content applications. Drawing on over a decade of experience with the industry-leading Opera® High Content Screening System, the Opera Phenix is designed for high-throughput, phenotypic screening and assays involving complex disease models, such as live cells, primary cells and microtissues.
IVIS Lumina XRMS 2D Optical Imaging System with Integrated X-ray

IVIS Lumina XRMS In Vivo Imaging System

Industry leading Fluorescence, Bioluminescence and X-Ray Imaging - All-In-One benchtop instrument! The IVIS® Lumina XRMS (x-ray multi-species optical imaging system) adds to the versatility of the IVIS Lumina XR by offering the flexibility to image large animals up to 500 grams with precise optical and X-Ray overlay.
Mantra benchtop

Mantra Quantitative Pathology Workstation

Mantra quantitative pathology workstation with inForm® image analysis software enables easy visualization, quantification and phenotyping of multiple types of immune cells simultaneously in intact FFPE tissue sections for cancer immunology research.
IVIS SpectrumBL High Throughput Optical Imaging System

IVIS SpectrumBL High-Throughput In Vivo Optical Imaging System

The IVIS® SpectrumBL is an advanced high-throughput 2D and 3D optical imaging system designed to improve quantitative outcomes of bioluminescent, chemiluminescent and Cerenkov in vivo imaging.
FMT In Vivo Imaging Instrument

FMT 4000 In Vivo Imaging System

The FMT 4000 fluorescence tomography imaging system provides the greatest utility of the FMT Systems with the ability to quantitate up to four fluorophores simultaneously. It comes with four excitation laser channels (635, 680, 750, & 790 nm).
Operetta CLS High Content Analysis Instrument

Operetta High-Content Imaging System

As scientists grapple with increasingly complex biological questions, they need to conduct larger, more complex imaging experiments. So they’re turning to the Operetta® High Content Imaging System – the ideal solution for analyzing the inner workings of healthy and diseased cells.
 
Quantum GX microCT Imaging System

Quantum GX microCT Imaging System

The Quantum GX microCT system has been replaced by the Quantum GX2 microCT imaging system. Please contact your local representative for further information, or visit the Quantum GX2 product page (Part Number - CLS149276).
G8 PET/CT benchtop scanner for preclinical imaging research

G8 PET/CT Preclinical Imaging System

Ultrasensitive and fast multimodal preclinical PET/CT imaging at your benchtop. The G-Platform offers Full Solutions for PET Imaging  and includes the G4 and G8 imaging systems.
IVIS SpectrumCT 2D/3D Optical/CT In Vivo Imaging System

IVIS SpectrumCT In Vivo Imaging System

The IVIS® SpectrumCT preclinical in vivo imaging system expands upon the versatility and advanced optical feature sets of the IVIS platform integrated with low dose microCT to support longitudinal imaging.
G4 Preclinical PET benchtop scanner with integrated X-ray

G4 PET/X-ray Preclinical Imaging System

Ultrasensitive and fast multimodal PET/X-ray imaging at your benchtop. The G-Platform offers and includes the G4 and G8 imaging systems.
Quantum GX2 microCT imaging system
New

Quantum GX2 microCT Imaging System

Image beyond bone – into oncology, cardiovascular and pulmonary diseases, and much more, with the Quantum GX2 microCT imaging system. With the Quantum GX2, flexibility is key. Combining the ability to perform high speed, low dose scans, ideal for longitudinal studies, across multiple species (mice, rats, rabbits) with high resolution ex vivo scanning, the Quantum GX2 microCT imaging system offers the flexibility and performance you need to not just image, but further understand your disease models.
IVIS Lumina HT High Throughput Benchtop 2D Optical Imaging System

IVIS Lumina III In Vivo Imaging System

The IVIS® Lumina Series III brings together years of leading optical imaging technologies into one easy to use and exquisitely sensitive bench-top system.
FMT In Vivo Imaging Instrument

FMT 2000 In Vivo Imaging System

The FMT 2000 is a workhorse 3D fluorescence tomographic system with the ability to quantitate up to two fluorophores simultaneously.
RediJect COX-2 Probe Standard Kit 133314

RediJect COX-2 Fluorescent Imaging Probe (Standard kit)

XenoLight RediJect COX-2 is a a novel fluorescent imaging probe for pre-clinical research that specifically detects the cyclooxygenase-2 (COX-2) biomarker noninvasively in vivo as well as in ex vivo tissue analysis applications. 
List Price : 680.00 CAD
PerkinElmer

Anti-DNP HRP Conjugate

Anti-DNP antibody conjugated to horseradish peroxidase
List Price : 340.00 CAD
TSA Tetramethylrhodamine System

TSA Tetramethylrhodamine System, for 100-300 Slides

TSA® tetramethylrhodamine (TMR) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra TMR in the localized area of the probe or antibody.
List Price : 850.00 CAD
RediJect COX-2 Probe Explorer Kit 133316

RediJect COX-2 Fluorescent Imaging Probe (Explorer kit)

XenoLight RediJect COX-2 is a a novel fluorescent imaging probe for pre-clinical research that specifically detects the cyclooxygenase-2 (COX-2) biomarker noninvasively in vivo as well as in ex vivo tissue analysis applications. 
List Price : 225.00 CAD
PerkinElmer

TSA Plus Cyanine 5

TSA® Plus Cyanine 5 (Cy5) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra Cy5 in the localized area of the probe or antibody.
Price Range : 260.00 CAD - 2100.00 CAD

AlphaLISA Human Programmed Cell Death Protein 1 (PD-1) Detection Kit

The AlphaLISA® Human PD-1 Detection Kit is designed for detection and quantitation of Human Programmed Cell Death Protein 1 (PD-1) in human serum, plasma, and cell culture supernatants using a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 790.00 CAD - 12300.00 CAD
PerkinElmer

Anti-DNP AP Conjugate

Anti-DNP antibody conjugated to alkaline phosphatase
List Price : 400.00 CAD
AlphaLISA immunoassay kits

BMP-7 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human BMP-7 enables the detection and quantitation of human BMP-7 in human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 540.00 CAD - 11900.00 CAD
Bioware Bioluminescent Oncology Cell LInes

Bioware® Brite Cell Line LL/2 Red-FLuc

Our bioluminescent light-producing oncology cell lines are labeled with luciferase or dual labeled with luciferase and fluorescent reporters (GFP) for in vivo studies.
AlphaLisa Analyte 2

HLA-E (human), lyophilized (AlphaLISA)

Human HLA-E standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA Human HLA-E Detection Kit, but can also be ordered separately.
List Price : 490.00 CAD
AlphaLISA immunoassay kits

Vimentin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human vimentin enables the quantitative determination of human vimentin in serum, buffered solution, and cell culture media using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 910.00 CAD - 17600.00 CAD

MMP-2 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Matrix Metalloproteinase-2 (MMP2) Detection Kit is designed for detection and quantitation of human MMP2 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay. The kit was designed to detect both MMP2 and pro-MMP2.
Price Range : 1850.00 CAD - 12300.00 CAD
TSA Biotin System

TSA Biotin System

TSA® biotin detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 380.00 CAD - 1250.00 CAD
AlphaLISA immunoassay kits

PD-L1 (human) AlphaLISA Detection Kit

The AlphaLISA® Human PD-L1 Detection Kit is designed for detection and quantitation of Human PD-L1 (CD274/B7-H1) in immunoassay buffer, human serum, plasma, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 850.00 CAD - 11900.00 CAD

CD86 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human CD86 enables the quantitative determination of human CD86 in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 730.00 CAD - 17600.00 CAD

ATP, [γ-33P]- 3000Ci/mmol, 10mCi/ml

Adenosine triphosphate, labeled on the gamma phosphate group with 33P.
Price Range : 540.00 CAD - 1800.00 CAD
RediJect COX-2 Control Kit 133349

RediJect COX-2 Fluorescent Imaging Probe (Control Dye)

RediJect COX-2 control dye is a non-reactive dye that can be used as a negative control when using the RediJect COX-2 probe. 
List Price : 225.00 CAD
AlphaLISA immunoassay kits

HVEM (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human herpesvirus entry mediator (HVEM) enables the quantitative determination of human HVEM (also known as TNFRSF14, CD270) in buffered solution and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 910.00 CAD - 17600.00 CAD
PerkinElmer

TSA Plus DIG Evaluation Kit

TSA® Plus DIG detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra DIG in the localized area of the probe or antibody.
Price Range : 280.00 CAD - 1850.00 CAD
PerkinElmer

TSA Fluorescein Reagent Pack

TSA® fluorescein reagent pack, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. These reagents amplify by depositing extra biotin in the localized area of the probe or antibody.
Price Range : 680.00 CAD - 3200.00 CAD

CTP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Cytidine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 560.00 CAD - 1850.00 CAD
AlphaLISA immunoassay kits

Trefoil factor 3 (human) AlphaLISA Detection Kit

The AlphaLISA® Human Trefoil Factor 3 (TFF3) Detection Kit is designed for detection and quantitation of human TFF3 in serum, buffered solution or cell culture medium in a homogeneous (no-wash steps, no separation steps) assay.
Price Range : 1850.00 CAD - 12300.00 CAD

dATP, [α-33P]- 3000Ci/mmol, 10mCi/ml

Deoxyadenosine triphosphate, labeled on the alpha phosphate group with 33P.
Price Range : 660.00 CAD - 1700.00 CAD
AlphaLISA immunoassay kits

COL1A1 (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human COL1A1 enables the detection and quantitation of human COL1A1 in serum, plasma, cell culture supernatants, cell lysates, and tissue homogenates using a homogeneous AlphaLISA assay (no wash steps).
Price Range : 540.00 CAD - 11900.00 CAD
AlphaLISA immunoassay kits

Laminin (human) AlphaLISA Detection Kit

The AlphaLISA® immunoassay kit for human laminin enables the detection and quantitation of human laminin in human serum, plasma, lysates, and cell culture supernatants using a homogeneous AlphaLISA assay (no wash steps). The assay shows no cross-reactivity with human IL-28A, IL-29, and Mouse Laminin.
Price Range : 540.00 CAD - 11900.00 CAD
In vivo Fluorescent Agents

OsteoSense 680EX Fluorescent Imaging Agent

Near-infrared (NIR) fluorescent agent for in vivo imaging and other applications. 
List Price : 620.00 CAD
TSA -Plus Tetramethylrhodamine System

TSA Plus TMR

TSA® Plus tetramethylrhodamine (TMR) detection kit, for amplification of signal in immunohistochemistry (IHC), immunofluorescence (IF) or in situ hybridization protocols. This kit amplifies by depositing extra TMR in the localized area of the probe or antibody.
Price Range : 480.00 CAD - 2100.00 CAD

MMP-3 (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human MMP-3 Detection Kit is designed for detection and quantitation of human matrix metalloproteinase-3 in cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 970.00 CAD - 12900.00 CAD
LANCE Detection Kit

Fibronectin (human) LANCE Ultra TR-FRET Detection Kit

The LANCE® Ultra Human Fibronectin Detection Kit is designed for detection and quantitation of human fibronectin in buffered solution and cell culture media using a homogeneous TR-FRET (no-wash steps, no separation steps) assay.
Price Range : 970.00 CAD - 12900.00 CAD
AlphaLisa Analyte 2

TIM-3 (human), lyophilized (AlphaLISA)

Human TIM-3 standard, for use in running standard curves in AlphaLISA assays. This standard is already provided in the AlphaLISA human TIM-3 Detection Kit, but can also be ordered separately.
List Price : 490.00 CAD
AlphaLisa Analyte 2

Alpha-1 Anti-Trypsin (A1AT) (human), lyophilized (AlphaLISA)

Human A1AT standard, lyophilized, for use in running standard curves in AlphaLISA no-wash immunoassays. This standard is already provided in the AlphaLISA Human A1AT Detection Kit, but can be ordered separately.
List Price : 290.00 CAD

"Cancer Immunotherapy & Immunology" 1-50 of 338 Products and Services

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